Best Answer: No. Valve has worked to ensure that Half-Life: Alyx is an amazing experience no matter what VR hardware you're playing on. Controllers with touch sensors will deliver a more "authentic" experience for Alyx's in-game hands. However, the actual gameplay won't be very different, even if you're still rocking a first-generation HTC Vive.
This is a companion discussion topic for the original entry at https://www.windowscentral.com/do-you-need-valve-knuckles-controllers-half-life-alyx